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Gene Information
Gene symbol: MTA2
Gene name: metastasis associated 1 family, member 2
HGNC ID: 7411
Synonyms: MTA1-L1
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
20636338
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We found that GATA-3 bound to metastasis-associated protein 2 (MTA-2), a component of the NuRD chromatin remodelling complex.
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2 |
20636338
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GATA-3 and MTA-2 in turn bound to several regulatory regions of the Th2 cytokine locus and the ifng promoter.
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3 |
20636338
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Cell transfection assay showed that MTA-2 acted as an antagonist with GATA-3 in the expression of Th2 cytokines, but co-operated with GATA-3 in the repression of the ifng gene expression.
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4 |
20636338
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These results suggest that GATA-3 interacts with MTA-2 to co-ordinately regulate Th2 cytokine and ifng loci during T helper cell differentiation.
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