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Gene Information
Gene symbol: RUNX3
Gene name: runt-related transcription factor 3
HGNC ID: 10473
Synonyms: AML2, PEBP2A3
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | GATA3 | 1 hits |
| 2 | IFNG | 1 hits |
| 3 | TBX21 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20399120 | Another T-box-containing transcription factor Eomes, but not T-bet, was induced both in GATA3-deficient CD4(+) T cells differentiated under Th2 cell conditions and in Th2 cells with enforced Runx3 expression, contributing to IFN-gamma production. |
| 2 | 20399120 | GATA3 overexpression blocked Runx3-mediated Eomes induction and IFN-gamma production, and GATA3 protein physically interacted with Runx3 protein. |
| 3 | 20399120 | Furthermore, we found that Runx3 directly bound to multiple regulatory elements of the Ifng gene and that blocking Runx3 function in either Th1 or GATA3-deficient "Th2" cells results in diminished IFN-gamma production by these cells. |