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Gene Information
Gene symbol: BIRC5
Gene name: baculoviral IAP repeat containing 5
HGNC ID: 593
Synonyms: EPR-1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD4 | 1 hits |
| 2 | CD86 | 1 hits |
| 3 | CD8A | 1 hits |
| 4 | HLA-A | 1 hits |
| 5 | IL6 | 1 hits |
| 6 | NCAM1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 12667293 | The DCs loading survivin activated T cells with higher CD4(+) T(H) ratio as compared with DCs group, T cells activated with DCs expressed CD8 and CD56. |
| 2 | 16482569 | In a Phase I clinical trial, we evaluated a vaccination with dendritic cells (DCs) loaded with a cocktail consisting of HLA-A*0201-restricted peptides derived from five different prostate cancer-associated antigens [prostate-specific antigen (PSA), prostate-specific membrane antigen (PSMA), survivin, prostein, transient receptor potential p8 (trp-p8)]. |
| 3 | 17471164 | Immunization of mice with Ad-surv DCs resulted in generation of CD8 T cells recognizing multiple epitopes from mouse survivin. |
| 4 | 18438666 | Two survivin peptides (SVN(57-64) and SVN(82-89)) generated specific CD8+ T cells. |
| 5 | 20930069 | Neutralization of IL-6 receptor on ECs abolished the ability of HCMV secretome to increase survivin expression and activated effector caspases. |
| 6 | 21705450 | In previous cancer vaccine clinical trials targeting survivin, induction of specific CD8(+) T-cell responses did not consistently lead to clinical responses. |
| 7 | 21705450 | The development of strategies to concurrently induce both CD4(+) and CD8(+) T-cell responses against survivin is warranted for optimal anti-survivin cancer immunotherapy. |
| 8 | 22078442 | There were five groups, which included survivin(4)/Th group, survivin(4)group, empty plasmid group, untransfected group and T lymphocytes group The expression of CD83 and CD86 on the surface of DCs, the expression of CD4 and CD8a on the surface of T lymphocytes, the apoptotic rates of MCF-7 cells after treated by DC vaccine were measured by flow cytometry; IFN-? levels of all groups were detected by ELISA and the growth inhibition of MCF-7 cells after being treated with DC vaccine was tested by MTT colorimetry. |