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Gene Information

Gene symbol: CD209

Gene name: CD209 molecule

HGNC ID: 1641

Synonyms: DC-SIGN, CDSIGN, DC-SIGN1, CLEC4L

Related Genes

#	Gene Symbol	Number of hits
1	CD4	1 hits
2	CD86	1 hits
3	CD8A	1 hits
4	IL10	1 hits
5	MRC1	1 hits
6	PTGS2	1 hits
7	SLAMF1	1 hits

Related Sentences

#	PMID	Sentence
1	15845642	We also show that BCG causes the impairment of IL-12 and the induction of IL-10 secretion by DC, irrespective of DC-SIGN expression.
2	17477875	Mature MDDC from healthy donors and cancer patients up-regulated the expression of CD83, CD86, frequencies of IL-12+ and COX-2+ cells, and secretion of IL-8; and down-regulated CD209 expression relative to their immature counterparts.
3	19648930	CD4(+) and CD8(+) T cells and a mixed population of plasmacytoid and myeloid dendritic cells (DCs), including cells expressing the C-type lectin receptor DC-SIGN, persisted at sites of HSV-2 reactivation for months after healing, even with daily antiviral therapy.
4	19648930	The CD4(+) T cells that persisted reacted to HSV-2 antigen, were enriched for expression of the chemokine receptor CCR5, and were contiguous to DCs expressing the interleukin-3 receptor CD123 or DC-SIGN.
5	19818504	Thus, we conclude that glycan modification of antigens and targeting to DC-SIGN enhance both CD4 and CD8 T cell responses.
6	21134826	Third, HBsAg can be internalized by DCs through the mannose receptor, which lacks the ability to induce DC maturation without the assistance of DC-SIGN.
7	21645571	Signaling lymphocyte activation molecule (SLAM) and dendritic cell-specific intercellular adhesion molecule-3 grabbing nonintegrin (DC-SIGN; CD209) are specific measles receptors: SLAM binds and permits entry of the virus into the cell, DC-SIGN acts as an attachment receptor, increasing viral binding efficiency and transmission.