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Gene Information
Gene symbol: IL23R
Gene name: interleukin 23 receptor
HGNC ID: 19100
Synonyms: IL-23R
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD28 | 1 hits |
| 2 | IFNG | 1 hits |
| 3 | IL12A | 1 hits |
| 4 | IL15 | 1 hits |
| 5 | IL17A | 1 hits |
| 6 | IL2 | 1 hits |
| 7 | IL23A | 1 hits |
| 8 | IL7 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20504940 | IL-23 receptor (IL-23R) blocking dramatically inhibited IL-22 production, but not IFN-gamma production. |
| 2 | 19386801 | Functional studies revealed that CD4+ IL-23R+ cells could be stimulated ex vivo with anti-CD3/CD28 to secrete both IL-17 and gamma interferon (IFN-gamma). |
| 3 | 19386801 | Functional evaluation of the expanded number of CD4+ IL-23R+ cells in the presence of different cytokines with anti-CD3/CD28 revealed that all cytokines used (IL-2, IL-7, IL-12, IL-15, and IL-23) increased the amount of IFN-gamma secreted by IL-23R+ CD4+ cells at different levels. |
| 4 | 19386801 | Our results indicate that IL-7 plus IL-12 was the optimum combination of cytokines for the expansion of IL-23R+ CD4+ cells and the secretion of IFN-gamma, while IL-12 preferentially stimulated these cells to secrete predominately IL-17. |