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Gene Information
Gene symbol: JUN
Gene name: jun proto-oncogene
HGNC ID: 6204
Synonyms: c-Jun, AP-1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | BTK | 1 hits |
| 2 | CD22 | 1 hits |
| 3 | GALT | 1 hits |
| 4 | HDAC9 | 1 hits |
| 5 | HMGB1 | 1 hits |
| 6 | HSPD1 | 1 hits |
| 7 | IFNG | 1 hits |
| 8 | IL13RA2 | 1 hits |
| 9 | IL6 | 1 hits |
| 10 | MAPK8 | 1 hits |
| 11 | NFKB1 | 1 hits |
| 12 | PDCD1 | 1 hits |
| 13 | SPG7 | 1 hits |
| 14 | TLR4 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 18331466 | Pharmacological suppression of p38 or extracellular signal-regulated kinase 1/2 mitogen-activated protein kinases with specific inhibitors failed to inhibit HSP65-induced HMGB1 release, but inhibition of c-Jun NH(2)-terminal kinase activation attenuated HMGB1 release. |
| 2 | 20068108 | IL-13 induced transforming growth factor-beta1 promoter activity in IL-13Ralpha2-positive tumor cells and in cells engineered to express IL-13Ralpha2 but not in IL-13Ralpha2-negative or RNA interference knockdown cells. c-Jun and c-Fos of the AP-1 family of nuclear factors were activated by IL-13 only in IL-13Ralpha2-positive cells. |
| 3 | 21059929 | The effect was antigen dose and time dependent, not associated with increased PD-1 expression or reduced calcium influx, but impaired Jun phosphorylation in response to TCR engagement. |
| 4 | 18228247 | The enhanced IL-6 production was dependent upon the activity of c-Jun kinase (JNK) and cFos. |
| 5 | 18228247 | The increased level of active JNK in dual-stimulated cells was accompanied by an increase in the level of active AP-1 monomers cJun and cFos. |
| 6 | 21147106 | In germinal center B cells of human GALT, Btk and Erk are phosphorylated, CD22 is down-regulated, Lyn is translocated to the cell membrane, and Fos and Jun are up-regulated; these features indicate B-cell receptor ligation during germinal center evolution. |
| 7 | 21450974 | PGN stimulates the activation of all three classes of MAPKs, extracellular signal-related kinase (ERK), c-Jun N-terminal kinase (JNK), and p38(mapk) in macrophages, albeit with differential activation kinetics. |
| 8 | 21477288 | Two types of c-jun inhibitors prevented increase of IL-13R?2 by HDAC inhibitors. |
| 9 | 21901556 | E. coli activates TLR4, which is responsible for the activation of IL-12, extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK). |
| 10 | 15925273 | We show that in vitro infection with Francisella tularensis results in activation of NF-kappaB, phosphorylation of p38 and c-Jun, and secretion of TNF-alpha in adherent mouse peritoneal cells, in the mouse macrophage-like cell line J774A.1, in the human macrophage cell line THP-1, and in human peripheral blood monocytic cells. |
| 11 | 20006311 | ESAT-6 reduced IFN-gamma mRNA levels by inhibiting the expression of the transcription factors, ATF-2, c-Jun and CREB, which upregulate IFN-gamma gene expression in T cells through binding to the IFN-gamma proximal promoter. |