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Gene Information
Gene symbol: LAMP1
Gene name: lysosomal-associated membrane protein 1
HGNC ID: 6499
Synonyms: CD107a
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CCL4 | 1 hits |
| 2 | CCR7 | 1 hits |
| 3 | CD27 | 1 hits |
| 4 | CD4 | 1 hits |
| 5 | CD8A | 1 hits |
| 6 | FAP | 1 hits |
| 7 | GZMB | 1 hits |
| 8 | IFNG | 1 hits |
| 9 | IL15 | 1 hits |
| 10 | IL17C | 1 hits |
| 11 | IL2 | 1 hits |
| 12 | TNF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15650058 | These results demonstrate that fusing Id to LAMP1 enhances CD8(+) and CD4(+) Id-specific responses for NHLs and may be useful therapeutically. |
| 2 | 16061874 | To enhance the immunogenicity of the mRNA-translated FAP product, a lysosomal targeting signal derived from lysosome-associated membrane protein-1 (LAMP-1) was fused to the COOH terminus of FAP to redirect the translated product into the class II presentation pathway. |
| 3 | 17641038 | Responding T cells expressed multiple functions including degranulation (CD107a surface mobilization) and production of IFN-gamma, IL-2, TNF-alpha, and MIP-1beta. |
| 4 | 17878354 | Release kinetics of the cytolytic effector molecules granzyme B and perforin, as well as the expression of the degranulation marker CD107a and IFN-gamma were simultaneously studied in SIV Gag(164-172) KP9-specific CD8+ T cells from Mane-A*10+ pigtail macaques. |
| 5 | 19903103 | We describe an extensive effort to optimize and validate quantitatively an in vitro T-cell culture method by determining the phenotype and function of both CD4(+) and CD8(+) T cells, including measurement of the phenotype markers CCR7, CD45RA, CD28 and CD27 and the functional markers interferon (IFN)-gamma, interleukin (IL)-2, macrophage inflammatory protein (MIP)-1beta, tumor necrosis factor (TNF)-alpha and CD107a. |
| 6 | 19342665 | DENV-specific CD8(+) T cells produced IFN-gamma, TNF-alpha, expressed cell surface CD107a, and exhibited cytotoxic activity in vivo. |
| 7 | 20719985 | These new HHV-8 epitopes activated monofunctional and polyfunctional CD8(+) T cells that produced various combinations of gamma interferon, interleukin 2, tumor necrosis factor alpha, macrophage inhibitory protein 1?, and cytotoxic degranulation marker CD107a in healthy HHV-8-seropositive individuals. |
| 8 | 18670213 | IL-21 and IL-15 upregulated CD107a and IFN-gamma, as well as NK cytotoxicity. |
| 9 | 21637109 | Cell lines were tested for their ability to produce effector molecules (CD107a, IL-2, IFN-?, TNF-?, perforin) and suppress virus replication in autologous CD4 T cells. |
| 10 | 18832706 | Polychromatic cytometry analysis indicated that the virus-specific T cells from the severe group tended to be a central memory phenotype (CD27(+)/CD45RO(+)) with a significantly higher frequency of polyfunctional CD4(+) T cells producing IFN-gamma, TNF-alpha, and IL-2, and CD8(+) T cells producing IFN-gamma, TNF-alpha, and CD107a (degranulation), as compared with the mild-moderate group. |