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Gene Information
Gene symbol: PTK2B
Gene name: PTK2B protein tyrosine kinase 2 beta
HGNC ID: 9612
Synonyms: CAKB, PYK2, RAFTK, PTK, CADTK
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD86 | 1 hits |
| 2 | MAPK3 | 1 hits |
| 3 | NFKB1 | 1 hits |
| 4 | RHOA | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21429240 | Additionally, pUS28 activated RhoA via Pyk2 in the U373 glioblastoma cells. |
| 2 | 18287580 | PorB was able to induce (i) protein tyrosine kinase (PTK) activity, (ii) the phosphorylation of Erk1 and Erk2, and (iii) IkappaB-alpha phosphorylation, leading to NF-kappaB nuclear translocation in B cells in a TLR2-dependent manner. |
| 3 | 18287580 | PorB-induced NF-kappaB nuclear translocation was not dependent on either PTK or Erk1/2 activities. |
| 4 | 18287580 | However, B-cell proliferation and the induction of increased surface expression of CD86 by PorB were dependent on PTK activity and not Erk1/2 activation. |