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Gene Information
Gene symbol: ABCC2
Gene name: ATP-binding cassette, sub-family C (CFTR/MRP), member 2
HGNC ID: 53
Synonyms: DJS, MRP2, cMRP
Related Genes
Related Sentences
# |
PMID |
Sentence |
1 |
11159731
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In summary, glibenclamide reversed MRP1-mediated drug resistance likely through inhibiting MRP1 activity and blocked organic anion efflux from MRP2-expressing hepatocytes.
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2 |
19356064
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Conversely, efflux transporters Mrp2, Mrp4, and Bcrp were increased 5.4-fold, 2-fold, and 1.6-fold, respectively in type 2 diabetic kidneys with no change in levels of Mrp1, Mrp5, or Pgp.
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3 |
19356064
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Studies of hepatic transporters in type 2 diabetic rats reveal that the protein level of Mrp5 was reduced to 4% of control livers with no change in levels of Bcrp, Mrp1, Mrp2, Mrp4, Ntcp, or Pgp.
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