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Gene Information

Gene symbol: ACO1

Gene name: aconitase 1, soluble

HGNC ID: 117

Synonyms: IRP1, IREBP

Related Genes

# Gene Symbol Number of hits
1 IGFBP1 1 hits
2 IGFBP3 1 hits
3 INS 1 hits

Related Sentences

# PMID Sentence
1 18566119 In this study, we show that IRE-BP1 interacts with the insulin response sequence of the IGF-I, IGFBP-1, and IGFBP-3 genes using chromatin immunoprecipitation assay.
2 18566119 Furthermore, activation by IRE-BP1 is sequence specific and mimics that of the insulin effect on gene transcription.
3 18566119 Tissue expression of IRE-BP1 is 50- to 200-fold higher in classical insulin target compared with nontarget tissues in lean animals, with a significantly reduced level of expression in the skeletal muscle and adipose tissue in obese and diabetic animals.