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Gene Information
Gene symbol: ANGPTL2
Gene name: angiopoietin-like 2
HGNC ID: 490
Synonyms: ARP2, HARP
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
21586562
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Here, we demonstrate that the expression of Angptl2 in epididymal adipose tissue of C57BL/6J mice shows pulsatility and circadian rhythmicity and that the rhythmicity was disrupted in high-fat-fed and leptin receptor-deficient diabetic db/db mice with insulin resistance.
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2 |
21586562
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In cultured adipocytes, recombinant Angptl2 increased adiponectin expression and stimulated insulin sensitivity partially by reducing the levels of tribbles homolog 3, a specific Akt kinase inhibitory protein.
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3 |
21586562
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Conversely, Angptl2 small interfering RNA reduced adiponectin expression, resulting in insulin resistance.
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4 |
21586562
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In preadipocytes, treatment with Angptl2 small interfering RNA inhibited differentiation to adipocytes and reduced adiponectin expression.
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