- About
- Home
- Introduction
- Statistics
- Programs
- Dignet
- Gene
- GenePair
- Help & Docs
- Documents
- Help
- FAQs
- Links
- Acknowledge
- Disclaimer
- Contact Us
Gene Information
Gene symbol: ARNT
Gene name: aryl hydrocarbon receptor nuclear translocator
HGNC ID: 700
Synonyms: HIF-1beta, bHLHe2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ADIPOQ | 1 hits |
| 2 | CYP1A1 | 1 hits |
| 3 | INS | 1 hits |
| 4 | IRS2 | 1 hits |
| 5 | PPP2R4 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21933986 | ChIP assays indicated that transcription factors FoxO1 and FoxO3a associated with the IRE on the IRS-2 promoter in ?-cells in a PI3K/PKB-dependent manner, whereas others, such as SREBP-1, the transcription factor binding to immunoglobulin heavy chain enhancer 3', and the aryl hydrocarbon receptor nuclear translocator (ARNT), did not. |
| 2 | 11809858 | AhR is a cytosolic ligand-dependent transcription factor that, in conjunction with the AhR nuclear translocator (Arnt), binds to dioxin response elements (DREs) located in the promoter region of target genes, such as CYP1A1, and induces their transcription. |
| 3 | 16098823 | ARNT expression is reduced in diabetic human islets and beta cell-specific ARNT knockout mice show the impaired glucose tolerance and abnormal insulin secretion that are characteristic of type 2 diabetes. |
| 4 | 18366646 | Common ARNT variants are unlikely to explain the linkage signal on chromosome 1q, but may alter insulin secretion in nondiabetic subjects. |
| 5 | 21635197 | Ceramide-dependent signaling involves activation of extracellularly regulated kinases 1 and 2 (ERK1/2), downregulation of Period (Per)-aryl hydrocarbon receptor nuclear translocator (Arnt)-single-minded (Sim) kinase (PASK), activation of okadaic-acid-sensitive protein phosphatase 2A (PP2A) and stimulation of NADPH-oxidase with generation of superoxides and lipid peroxides. |
| 6 | 21873554 | Mice with adipocyte-specific targeted disruption of the genes encoding the HIF1 obligatory subunits Hif1? or Arnt (Hif1?) were generated using an aP2-Cre transgene with the Cre/LoxP system. |
| 7 | 21873554 | On an HFD, adipocyte-specific ARNT knockout mice and adipocyte-specific HIF1? knockout mice exhibit similar metabolic phenotypes, including reduced fat formation, protection from HFD-induced obesity, and insulin resistance compared with similarly fed wild-type controls. |