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Gene Information

Gene symbol: ARX

Gene name: aristaless related homeobox

HGNC ID: 18060

Synonyms: ISSX, CT121, EIEE1

Related Genes

# Gene Symbol Number of hits
1 PAX4 1 hits
2 PDX1 1 hits
3 TLE3 1 hits

Related Sentences

# PMID Sentence
1 22056672 Furthermore, we demonstrate that Nkx2.2 preferentially recruits Grg3 and HDAC1 to the methylated Aristaless homeobox gene (Arx) promoter in ? cells.
2 16772326 Correspondingly, SREBP-1c DN largely corrected decreases in the expression of the transcription factors Pdx-1 and MafA but did not affect the abnormalities in Pax6, Arx, hepatic nuclear factor-1alpha (HNF1alpha), HNF3beta/Forkhead box-a2 (Foxa2), inducible cyclic AMP early repressor (ICER), or transcription factor 7-like 2 (TCF7L2) expression observed in ZDF islets.
3 19665969 We have previously reported that the loss of Arx and/or Pax4 gene activity leads to a shift in the fate of the different endocrine cell subtypes in the mouse pancreas, without affecting the total endocrine cell numbers.