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Gene Information
Gene symbol: BIRC2
Gene name: baculoviral IAP repeat containing 2
HGNC ID: 590
Synonyms: cIAP1, hiap-2, MIHB, RNF48, c-IAP1
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
21491265
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The molecular targets involved in chemoprevention like the inhibition of NF-?B activation via impairing nuclear translocation, suppresses cIAP1 expression, increases caspase-3/7 activation, arrests cell cycle in G2 + M phases, up-regulates Cytochrome-c, Apaf-1, activates PI3K/Akt/I kappaB kinases IKK, suppresses cell proliferation, and inducts apoptosis and chromatin condensation.
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