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Gene Information

Gene symbol: CCNA2

Gene name: cyclin A2

HGNC ID: 1578

Related Genes

# Gene Symbol Number of hits
1 AVP 1 hits
2 CCK 1 hits
3 CCND1 1 hits
4 PDX1 1 hits
5 SKP2 1 hits
6 SST 1 hits
7 WNT10A 1 hits

Related Sentences

# PMID Sentence
1 15146007 Ki-67 and cyclin A LIs were associated with the presence of a heavy inflammatory reaction and diabetes insipidus, but did not correlate with the long term risk of tumour regrowth.
2 15896901 We conclude that treatment of thyrotropic TtT-97 tumors with T3 resulted in the decreased expression of Wnt-10A, and that thyroid hormone may inhibit growth via cyclin A regulation.
3 16223861 This led to the hypothesis that TH, acting through increased type 5 somatostatin receptor, could activate the ERK pathway leading to cAMP response element binding protein-dependent decreased expression of critical cell cycle proteins, specifically cyclin A, resulting in hypophosphorylation of Rb and its subsequent arrest of S-phase progression.
4 18544709 CBP-S436A islets exhibited elevated cyclin A2, reduced p27, and no changes in D-type cyclins, PDX-1, or Skp2.
5 18544709 PDX-1 knockdown reduced exendin-4-stimulated cAMP synthesis and cyclin A2 transcription.
6 18544709 Cyclin A2 is required for beta-cell proliferation, exendin-4 stimulates cyclin A2 expression via the cAMP pathway, and exendin-4 stimulation of cAMP requires PDX-1.
7 18845673 Analysis of cyclin and cdk mRNA and protein abundance revealed that CCK overexpression increased cyclin A, cyclin B, cyclin E, cdk1, and cdk2 with no change in cyclin D1, cyclin D2, cyclin D3, cdk4, or cdk6 in mouse and human islets.