- About
- Home
- Introduction
- Statistics
- Programs
- Dignet
- Gene
- GenePair
- Help & Docs
- Documents
- Help
- FAQs
- Links
- Acknowledge
- Disclaimer
- Contact Us
Gene Information
Gene symbol: CDKN1C
Gene name: cyclin-dependent kinase inhibitor 1C (p57, Kip2)
HGNC ID: 1786
Synonyms: P57, KIP2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CDK4 | 1 hits |
| 2 | H19 | 1 hits |
| 3 | IGF2 | 1 hits |
| 4 | KCNQ1OT1 | 1 hits |
| 5 | PDX1 | 1 hits |
| 6 | POMC | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 11813134 | The most common constitutional abnormalities in BWS are epigenetic, involving abnormal methylation of either H19 or LIT1, which encode untranslated RNAs on 11p15. |
| 2 | 11813134 | These results define an epigenotype-phenotype relationship in BWS, in which aberrant methylation of H19 and LIT1 and UPD are strongly associated with cancer risk and specific birth defects. |
| 3 | 17413842 | Several genes in this imprinted cluster encode proteins involved in growth regulation, e.g. the paternally expressed IGF2 and the maternally expressed cell-cycle regulator cyclin dependent kinase inhibitor, CDKN1C. |
| 4 | 19576197 | When the MafA transgene is expressed in Pdx1+ pancreatic progenitors, both pancreatic mass and proliferation of progenitors are reduced, at least partially due to induction of cyclin kinase inhibitors p27 and p57. |
| 5 | 21536883 | Molecular analyses in vitro and in vivo showed that R-roscovitine suppresses ACTH expression, induces corticotroph tumor cell senescence and cell cycle exit by up-regulating p27, p21 and p57, and downregulates cyclin E expression. |
| 6 | 15821902 | CDK4 activity is inhibited by CDKN1C, which is regulated by insulin. |