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Gene Information
Gene symbol: DGAT2L4
Gene name: diacylglycerol O-acyltransferase 2-like 4
HGNC ID: 23251
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | HLA-B | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17632406 | Here we provide evidence that: 1) tryptophan conversion to kynurenines is activated in DCs by cytotoxic T lymphocyte antigen 4, both in a soluble form or anchored to the regulatory T cell (Treg) membrane; 2) an increased IDO-dependent tolerogenesis correlates with the inhibition of DAP12 functions, an adapter molecule associated with activating receptors; 3) a tolerogenic phenotype can be acquired by DCs lacking functional IDO through the paracrine production of kynurenines by IDO-competent DCs; 4) the suppressive effect of Treg generated in a microenvironment with low tryptophan concentration and a mixture of kynurenines can protect mice in an experimental model of fulminant diabetes. |