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Gene Information
Gene symbol: ESR1
Gene name: estrogen receptor 1
HGNC ID: 3467
Synonyms: NR3A1, Era
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AR | 1 hits |
| 2 | INS | 1 hits |
| 3 | NOS3 | 1 hits |
| 4 | PRKAA1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17513703 | It appears likely that ESR1 contributes to type 2 diabetes and CVD risk via pleiotropic effects, leading to insulin resistance, a poor lipid profile, and obesity. |
| 2 | 18438173 | Estrogen receptor alpha in osteoclasts appears to regulate bone resorption in women but not men, whereas androgen receptor signalling in osteoblasts may only partly regulate bone resorption in males. |
| 3 | 18256928 | Stimulation of AMPK by metformin resulted in a significant repression of cell proliferation and active MAPK1/2 in both estrogen receptor alpha (ERalpha) negative (MDA-MB-231, MDA-MB-435) and positive (MCF-7, T47D) human breast cancer cell lines. |
| 4 | 19157583 | Estrogen receptor alpha (ERalpha) mediates beneficial actions on endothelial nitric oxide synthase (eNOS) and cholesterol metabolism. |