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Gene Information

Gene symbol: GPER

Gene name: G protein-coupled estrogen receptor 1

HGNC ID: 4485

Synonyms: FEG-1, GPCR-Br, LERGU, LERGU2, DRY12, LyGPR, CEPR

Related Genes

# Gene Symbol Number of hits
1 ESR2 1 hits
2 INS 1 hits
3 MAPK1 1 hits
4 SST 1 hits

Related Sentences

# PMID Sentence
1 20634925 E(2) signals via the classical estrogen receptor (ER)alpha and ERbeta, an extranuclear form of ERalpha and the G protein-coupled estrogen receptor (GPER).
2 21521748 Confocal microscopy revealed GPR30 expression in islet insulin, glucagon, and somatostatin cells.
3 21673097 GPER is expressed in MIN6 cells, where estradiol and the GPER-selective agonist G-1 mediate calcium mobilization and activation of ERK and phosphatidylinositol 3-kinase.
4 21673097 Our results indicate that GPER activation of the epidermal growth factor receptor and ERK in response to estradiol treatment plays a critical role in the secretion of insulin from ?-cells.