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Gene Information
Gene symbol: GSTA4
Gene name: glutathione S-transferase alpha 4
HGNC ID: 4629
Related Genes
Related Sentences
# |
PMID |
Sentence |
1 |
21929724
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This review highlights the significance of the mitochondrial GST pool, particularly the mechanism and significance of dual targeting of GSTA4-4 under in vitro and in vivo conditions.
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2 |
20150287
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The objective of this study was to evaluate the expression of GSTA4 and the role(s) of protein carbonylation in adipocyte function.
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3 |
20150287
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GSTA4 expression is selectively downregulated in adipose tissue of obese insulin-resistant C57BL/6J mice and in human obesity-linked insulin resistance.
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4 |
20150287
|
These results indicate that downregulation of GSTA4 in adipose tissue leads to increased protein carbonylation, ROS production, and mitochondrial dysfunction and may contribute to the development of insulin resistance and type 2 diabetes.
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