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Gene Information
Gene symbol: GTF3A
Gene name: general transcription factor IIIA
HGNC ID: 4662
Synonyms: TFIIIA, AP2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ACOX1 | 1 hits |
| 2 | ADIPOQ | 1 hits |
| 3 | IL6 | 1 hits |
| 4 | PPARG | 1 hits |
| 5 | PPT1 | 1 hits |
| 6 | TNF | 1 hits |
| 7 | WARS | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 1372897 | For aP2, the effect requires long chain fatty acids and occurs without a generalized activation of the genes linked to adipocyte differentiation. |
| 2 | 10799317 | Rosiglitazone increased adipose tissue aP2 mRNA in both models while increasing liver acyl CoA oxidase mRNA in db/db mice but not in fatty Zucker rats. |
| 3 | 12927809 | We examined the role of PPAR gamma 2 and C/EBP alpha for adiponectin and aP2 gene activation in C/EBP alpha(-/-) fibroblasts by stably expressing PPAR gamma 2 or C/EBP alpha. |
| 4 | 12927809 | Several observations showed that the adiponectin and aP2 genes can be differentially regulated in adipocytes: (1) Topiramate, an anti-epileptic agent with weight-reducing properties, increased adiponectin mRNA levels and secretion, but did not, like the thiazolidinediones, increase aP2 expression; (2) IL-6 reduced adiponectin, but significantly increased, aP2 expression; and (3) TNFalpha inhibited adiponectin, but paradoxically increased, aP2 expression in PPAR gamma 2-infected C/EBP alpha null cells. |
| 5 | 16394521 | PPT enhanced adipogenesis by increasing the expression of PPARgamma target genes such as aP2, LPL and PEPCK. |
| 6 | 21219874 | As a result of the artepillin C-induced adipocyte differentiation, the gene expression of PPAR? and its target genes, such as aP2, adiponectin and glucose transporter (GLUT) 4, was increased. |
| 7 | 20363877 | The widely used aP2 promoter cassette, which is frequently chosen to achieve adipocyte-specific expression of transgenes, conveys transcription in cell types other than adipocytes, such as macrophages and cardiomyocytes. |
| 8 | 17681146 | Both effects are accompanied by corresponding changes in the expression of PPARgamma, C/EBPalpha, and genes marking terminal adipocyte differentiation, including Glut4, aP2, and fatty acid synthase. |