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Gene Information
Gene symbol: H2AFX
Gene name: H2A histone family, member X
HGNC ID: 4739
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ATM | 1 hits |
| 2 | ATR | 1 hits |
| 3 | EDN1 | 1 hits |
| 4 | EP300 | 1 hits |
| 5 | PIK3CG | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 19903865 | Histone H2AX phosphorylation and lysine acetylation were examined for oxidative DNA damage and p300 activation. |
| 2 | 19903865 | HUVECs in 25 mmol/l glucose showed increased p300 production accompanied by increased binding of p300 to ET-1 and FN promoters, augmented histone acetylation, H2AX phosphorylation, activation of multiple transcription factors, and increased mRNA expression of vasoactive factors and ECM proteins. p300 overexpression showed a glucose-like effect on the mRNA expression of ET-1, VEGF, and FN. |
| 3 | 20736911 | This phosphorylation of H2AX is mediated by the phosphatidyl-inosito 3-kinase (PI3K) family of proteins, ataxia telangiectasia mutated (ATM), DNA-protein kinase catalytic subunit and ATM and RAD3-related (ATR). |