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Gene Information

Gene symbol: IL5

Gene name: interleukin 5 (colony-stimulating factor, eosinophil)

HGNC ID: 6016

Synonyms: IL-5, EDF, TRF

Related Genes

# Gene Symbol Number of hits
1 CD4 1 hits
2 CD8A 1 hits
3 IFNG 1 hits
4 IL15 1 hits
5 IL17A 1 hits
6 IL18 1 hits
7 IL2 1 hits
8 IL25 1 hits
9 IL4 1 hits
10 IL6 1 hits
11 IL7 1 hits
12 IL8 1 hits
13 SPN 1 hits

Related Sentences

# PMID Sentence
1 22103849 IL-25 drives the expression of IL-4, IL-5, and IL-13, thereby contributing to allergic disease.
2 8105989 Results indicate that 1) cytokine mRNA profiles exhibited by islet-infiltrating cells of female and male NOD mice were quite similar with the exception of IL-6 expression and the marked differences in the levels of IL-2 receptor and IL-1 alpha mRNA, 2) CD4+ T lymphocytes expressed IL-4, presumably IL-5, and occasionally IL-10 mRNA but no detectable IL-2 mRNA, 3) CD8+ T lymphocytes exhibited TNF-beta, perforin and high levels of IFN-gamma, and 4) IL-7 was expressed in the islet at very high levels.
3 14525620 The 29 known interleukins were clustered into three groups: noxious (the "bad", 8 members), comprising IL-1, IL-2, IL-6, IL-7, IL-8, IL-15, IL-17 and IL-18; protective (the "good", 5 members), comprising IL-4, IL-10, IL-11, IL-12 and IL-13; and "aloof", comprising IL-5, IL-9, IL-14, IL-16 and IL-19 through IL-29 (15 members).
4 15979891 In 62 GDM patients and 74 women with normal glucose tolerance (NGT), and their babies, we assessed total lymphocytes, T lymphocyte subsets CD3 and CD8 expressing T cell receptor (TCR) alpha/beta or gamma/delta, CD16 and CD19, pancreatic autoantibodies and cytokines (IL-5, IL-2, soluble receptor IL-2).
5 18490738 Nonetheless, the CD43(-/-) mice produced more IL-5 when restimulated with MOG(35-55) in vitro and demonstrated decreased delayed-type hypersensitivity responses.
6 19382103 Cytokines and chemokines were detected in cell-culture supernatants by protein microarray (naive T-cells; interleukin (IL)-7, Th1; interferon-gamma, tumour necrosis factor-beta, Th2; IL-5, Th3; transforming growth factor-beta, T-regulatory cell type 1; IL-10 and inflammatory cytokines; tumour necrosis factor-alpha, IL-6 and chemokines; monocyte chemoattractant protein-1, monokine upregulated by IFN-gamma) in relation to clinical outcome (C-peptide).