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Gene Information
Gene symbol: MBP
Gene name: myelin basic protein
HGNC ID: 6925
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | F2 | 1 hits |
| 2 | HLA-A | 1 hits |
| 3 | HSP90B1 | 1 hits |
| 4 | HSPD1 | 1 hits |
| 5 | IFNG | 1 hits |
| 6 | INS | 1 hits |
| 7 | MS | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 1717849 | We have generated transgenic mice that express class I H-2Kb MHC molecules, under the control of the myelin basic protein promoter, specifically in oligodendrocytes. |
| 2 | 7505909 | Insulin treatment normalizes glycemia levels, partially counteracts P0 mRNA increase at both stages of diabetes and delays MBP mRNA increase present only in chronic animals. |
| 3 | 7515882 | Insulin and TPA also stimulated MAPK (> 2-fold increase over basal, with myelin basic protein as a substrate). |
| 4 | 11509551 | In this study, we tested the hypothesis that insulin via the nitric oxide (NO)/cGMP pathway may inactivate Rho, resulting in a decrease in phosphorylation of the myosin-bound subunit (MBS(Thr695)) of MBP and in its activation. |
| 5 | 11509551 | Treatment of confluent serum-starved VSMCs with insulin prevented thrombin-induced increases in membrane-associated RhoA, Rho kinase activation, and site-specific phosphorylation of MBS(Thr695) of MBP and caused MBP activation. |
| 6 | 11739394 | Recent studies from our laboratory have shown that insulin stimulates myosin-bound phosphatase (MBP) in vascular smooth muscle cells (VSMCs) by decreasing site-specific phosphorylation of the myosin-bound subunit (MBS) of MBP via nitric oxide/cGMP-mediated Rho/Rho kinase inactivation. |
| 7 | 11971030 | In this study, we show that the IgG-Ag retroviral constructs, expressing myelin basic protein (MBP) or glutamic acid decarboxylase in B cells, can be used for the treatment of murine models for multiple sclerosis and diabetes. |
| 8 | 11369711 | Lymphocytes from mice treated orally with MBP and IL-10 proliferated less, and produced decreased amounts of IFN-gamma and IL-2 and increased amounts of IL-10 and transforming growth factor-beta upon in vitro stimulation with MBP. |
| 9 | 15039392 | Immunization with high doses of gp96 prevents myelin basic protein- or proteolipid protein-induced autoimmune encephalomyelitis in SJL mice and the onset of diabetes in non-obese diabetic mice. |
| 10 | 21903338 | This article considers the subset of autoimmunity-related autism patients and postulates that MAP, through molecular mimicry to its heat shock protein HSP65, triggers autism by stimulating antibodies that cross react with myelin basic protein (MBP). |