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Gene Information
Gene symbol: MIRN146A
Gene name: microRNA 146a
HGNC ID: 31533
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | IL6 | 1 hits |
| 2 | INS | 1 hits |
| 3 | TNF | 1 hits |
| 4 | TRAF6 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21249428 | We sought to evaluate the role of miR-146a expression along with its downstream proinflammatory signals in relation to glycemic control and insulin resistance. |
| 2 | 21249428 | Among the target genes of miR-146a, TRAF-6 mRNA expression was significantly increased in patients with Type 2 diabetes while there was no significant difference in the mRNA levels of IRAK1 in the study groups. |
| 3 | 21249428 | While SOCS-3 mRNA levels increased, plasma TNF? and IL-6 levels were also significantly higher in patients with type 2 diabetes. miR-146a expression was negatively correlated to glycated hemoglobin, insulin resistance, TRAF6, and NF?B mRNA levels and circulatory levels of TNF? and IL-6. |
| 4 | 21249428 | Reduced miR-146a levels are associated with insulin resistance, poor glycemic control, and several proinflammatory cytokine genes and circulatory levels of TNF? and IL-6 in Asian Indian Type 2 diabetic patients. |
| 5 | 20086228 | We found that IL-1beta and TNF-alpha induce the expression of miR-21, miR-34a, and miR-146a both in MIN6 cells and human pancreatic islets. |