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Gene Information

Gene symbol: NCK1

Gene name: NCK adaptor protein 1

HGNC ID: 7664

Synonyms: NCKalpha

Related Genes

# Gene Symbol Number of hits
1 INS 1 hits
2 IRS1 1 hits
3 MAPK1 1 hits

Related Sentences

# PMID Sentence
1 7626133 Tyrosine-phosphorylation of IRS-1 causes it to associate with the src-homology-2 (SH2) domains of at least four other proteins: phosphatidylinositol 3'-kinase (PI3K), growth factor receptor-bound protein-2 (GRB2), Nck, and Syp.
2 7485492 Phosphorylated IRS-1 then interacts with the p85 alpha subunit of phosphatidylinositol 3-kinase (PI3K), Nck, growth factor receptor-bound protein 2 (GRB2), and Syp, thus branching insulin's signal for both mitogenic and metabolic responses.
3 12730241 Insulin receptor-phosphorylated IRS5/DOK4 associates with RasGAP, Crk, Src, and Fyn, but not phosphatidylinositol 3-kinase p85, Grb2, SHP-2, Nck, or phospholipase Cgamma Src homology 2 domains, and activates MAPK in cells.