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Gene Information
Gene symbol: NCOA1
Gene name: nuclear receptor coactivator 1
HGNC ID: 7668
Synonyms: SRC1, F-SRC-1, NCoA-1, KAT13A, RIP160, bHLHe74
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | HNF4A | 1 hits |
| 2 | NR1I2 | 1 hits |
| 3 | PPARG | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21920351 | We show that metformin disrupts PXR's interaction with steroid receptor coactivator-1 (SRC1) in a two-hybrid assay independently of the PXR ligand binding pocket. |
| 2 | 14982928 | To further assess potential mechanisms of activation, we have solved a structure of human HNF-4alpha bound to both fatty acid ligand and a coactivator sequence derived from SRC-1. |
| 3 | 19485965 | These findings suggest that strategies aimed at increasing SRC-1 expression and recruitment to PPARgamma upon aging might help improve age-associated metabolic disorders. |