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Gene Information
Gene symbol: NQO1
Gene name: NAD(P)H dehydrogenase, quinone 1
HGNC ID: 2874
Synonyms: DHQU, QR1, DTD
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ALDH2 | 1 hits |
| 2 | CAT | 1 hits |
| 3 | CD14 | 1 hits |
| 4 | CYB5A | 1 hits |
| 5 | CYP2B6 | 1 hits |
| 6 | GCG | 1 hits |
| 7 | IL6 | 1 hits |
| 8 | LBP | 1 hits |
| 9 | NFE2L2 | 1 hits |
| 10 | SOCS3 | 1 hits |
| 11 | TLR4 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 6217856 | This azoreductase activity was inhibited by cyanide and cytochrome b5 antibody, but was resistant to carbon monoxide and SKF-525A (beta-diethylaminoethyl-diphenylpropylacetate). 2. |
| 2 | 6217856 | No direct correlation could be established between the variations of azoreductase activity and those of cytochromes P-450 and b5, and of NADPH-cytochrome P-450 reductase in these experimental situations. |
| 3 | 10812837 | Investigation of such situations has generated data implicating GSTT1, GSTM1, NAT2, and NQO1 polymorphisms in biological monitoring of some chemicals; the ALDH2 polymorphism is the likely link between the genotype and the metabolism of low molecular aliphatic aldehydes. |
| 4 | 20448207 | Expression analysis revealed that GLP-1 can induce the oxidative defense genes HO-1 and NQO1. |
| 5 | 20227863 | AGE-BSA (100 ?g ml?¹, 0-24 h), but not native BSA, elicited time-dependent increases in ROS generation, Nrf2 nuclear translocation and enhanced mRNA and protein expression of HO-1 and NQO1, but not glutathione peroxidase-1. |
| 6 | 21217061 | High-glucose-induced upregulation of NQO1, GCLC, and HMOX1 was also prevented by pretreatment with polyethylene glycol (PEG)-catalase or N-acetylcysteine, whereas administration of H(2)O(2) mimicked the effect of high glucose. |
| 7 | 21289251 | Indices of oxidative stress, inflammation, Nrf-2 binding activity, the concentrations of endotoxin (lipopolysaccharide) and lipoprotein binding protein (LBP), and the expression of toll-like receptor 4 (TLR-4), CD14, IL-1?, TNF?, SOCS-3, Keap-1, NAD(P)H:quinone oxidoreductase-1 (NQO-1), and GST-P1 were measured. |
| 8 | 21289251 | The intake of the supplement suppressed the meal-induced elevations of plasma endotoxin and LBP concentrations, the expression of p47(phox), TLR-4, CD14, SOCS-3, IL-1?, and Keap-1, while enhancing Nrf-2 binding activity and the expression of NQO-1 and GST-P1 genes. |
| 9 | 21289251 | It also stimulates specific Nrf-2 activity and induces the expression of the related antioxidant genes, NQO-1 and GST-P1. |
| 10 | 21457706 | At the transcriptional levels, metformin treatment caused significant restoration in diabetic nephropathy-induced oxidative stress mRNA levels, particularly GST?, NQO1, and CAT genes, whereas inhibited TNF-? and IL-6 pro-inflammatory genes. |