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Gene Information
Gene symbol: NTS
Gene name: neurotensin
HGNC ID: 8038
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AGRP | 1 hits |
| 2 | ARC | 1 hits |
| 3 | CCK | 1 hits |
| 4 | CYSLTR2 | 1 hits |
| 5 | FOS | 1 hits |
| 6 | GAL | 1 hits |
| 7 | LEP | 1 hits |
| 8 | MLN | 1 hits |
| 9 | NPY | 1 hits |
| 10 | PPY | 1 hits |
| 11 | SST | 1 hits |
| 12 | VIPR1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 6124374 | For instance, cholecystokinin and human pancreatic polypeptide (hPP) may be importantly involved in the regulation of appetite and satiety control and the development of obesity whereas somatostatin, "endorphins", and neurotensin may directly or indirectly modulate islet hormone secretion. |
| 2 | 2227272 | Motilin was elevated in 29%, human pancreatic polypeptide in 27%, neurotensin in 20%, and gastrin-releasing peptide in 10%, whereas insulin, glucagon, and somatostatin were not elevated in any patient. |
| 3 | 7912431 | The reported VIP receptor antagonist, neurotensin(6-11)-VIP(7-28), was also an agonist. |
| 4 | 10657511 | Neuropeptide Y (NPY), melanin concentrating hormone (MCH), orexins A and B, galanin, and agouti -related peptide (AgRP) all act to stimulate feeding while alpha-melanocyte stimulating hormone (alphaMSH), corticotropin releasing hormone (CRH), cholecystokinin (CCK), cocaine and amphetamine regulated transcript (CART), neurotensin, glucagon-like peptide 1 (GLP 1), and bombesin have anorectic actions.(1) Leptin, expressed in the periphery in white adipose tissue, acts in the CNS to modulate the expression of several of these hypothalamic peptides.(1) This creates a functional link between the adipose tissue and the brain that translates the information on body fat provided by leptin to input into energy balance regulating processes. |
| 5 | 16505217 | We show here that in contrast to POMC neurons in the ARC, leptin does not stimulate phosphorylation of signal-transducer and activator of transcription 3 in NTS POMC neurons of POMC-EGFP reporter mice. |
| 6 | 16505217 | In addition, leptin does not induce c-Fos expression in NTS POMC neurons unlike ARC POMC neurons. |
| 7 | 19679549 | Treatment of human pancreatic cancer cells (PANC-1, MIAPaCa-2, and BxPC-3) with insulin (10 ng/mL) for 5 minutes markedly enhanced the increase in intracellular [Ca(2+)] induced by GPCR agonists (e.g., neurotensin, bradykinin, and angiotensin II). |