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Gene Information
Gene symbol: PMCH
Gene name: pro-melanin-concentrating hormone
HGNC ID: 9109
Synonyms: MCH
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | GHRL | 1 hits |
| 2 | GRP | 1 hits |
| 3 | HCRT | 1 hits |
| 4 | IAPP | 1 hits |
| 5 | INS | 1 hits |
| 6 | LEP | 1 hits |
| 7 | POMC | 1 hits |
| 8 | PYY | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 9519731 | POMC mRNA was negatively correlated with both neuropeptide Y (NPY) and melanin-concentrating hormone (MCH) mRNA. |
| 2 | 15159168 | MCH neurons may be regulated by leptin, insulin and glucose. |
| 3 | 16697020 | Within the lateral hypothalamic area, amylin diminishes the expression of orexigenic neuropeptides such as orexin and MCH. |
| 4 | 16935329 | The structure and function of many hypothalamic peptides (neuropeptide Y (NPY), melanocortins, agouti-related peptide (AGRP), cocaine and amphetamine regulated transcript (CART), melanin concentrating hormone (MCH), orexins have been characterized in rodent models The peripheral neuropeptides such as cholecystokinin (CCK), ghrelin, peptide YY (PYY3-36), amylin, bombesin regulate important gastrointestinal functions such as motility, secretion, absorption, provide feedback to the central nervous system on availability of nutrients and may play a part in regulating food intake. |
| 5 | 12239605 | Orexin (1 nmol/mouse) significantly increased oxygen consumption, while MCH (1 nmol/mouse) had no significant effect compared to ACSF-treated controls. |
| 6 | 17259374 | Interestingly, MCH enhanced insulin secretion in human and mouse islets and rodent beta-cell lines in a dose-dependent manner. |