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Gene Information
Gene symbol: PREB
Gene name: prolactin regulatory element binding
HGNC ID: 9356
Synonyms: SEC12
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
19382911
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Prolactin regulatory element-binding (PREB) protein has been identified as a factor that regulates insulin gene expression in the pancreas.
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2 |
19382911
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In the cells expressing or knocking down the PREB, ApN expression was determined.
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3 |
19382911
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The nuclear extract contained ApN promoter-binding activity that was super-shifted by PREB antiserum in EMSA studies.
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4 |
19382911
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A deletional analysis of the ApN promoter showed that the PREB-responsive cis-element in the ApN promoter mediated the transcriptional effect of PREB, whereas a mutant of this motif in the ApN promoter abrogated the effect of PREB, as well as that of cAMP.
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5 |
19382911
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Furthermore, cells expressing or knocking down PREB exhibited decreased and increased ApN expression, respectively.
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