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Gene Information

Gene symbol: PREB

Gene name: prolactin regulatory element binding

HGNC ID: 9356

Synonyms: SEC12

Related Genes

# Gene Symbol Number of hits
1 ANPEP 1 hits
2 INS 1 hits

Related Sentences

# PMID Sentence
1 19382911 Prolactin regulatory element-binding (PREB) protein has been identified as a factor that regulates insulin gene expression in the pancreas.
2 19382911 In the cells expressing or knocking down the PREB, ApN expression was determined.
3 19382911 The nuclear extract contained ApN promoter-binding activity that was super-shifted by PREB antiserum in EMSA studies.
4 19382911 A deletional analysis of the ApN promoter showed that the PREB-responsive cis-element in the ApN promoter mediated the transcriptional effect of PREB, whereas a mutant of this motif in the ApN promoter abrogated the effect of PREB, as well as that of cAMP.
5 19382911 Furthermore, cells expressing or knocking down PREB exhibited decreased and increased ApN expression, respectively.