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Gene Information
Gene symbol: PTBP1
Gene name: polypyrimidine tract binding protein 1
HGNC ID: 9583
Synonyms: HNRPI, HNRNP-I, PTB2, PTB3, PTB-1, PTB4, pPTB
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ADIPOR1 | 1 hits |
| 2 | APPL1 | 1 hits |
| 3 | INS | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 11606564 | These results suggest that inhibition of PTB domain function in IRS-1 by phosphorylation of Ser(307) (Ser(312) in human IRS-1) might be a general mechanism to regulate insulin signaling. |
| 2 | 17287464 | Proteomic analysis demonstrated that the cytoplasmic tails of both AdipoR1 and -R2 interacted with APPL1, an adaptor protein that contains a PH (pleckstrin homology) domain, a PTB (phosphotyrosine-binding) domain, and a Leucine zipper motif. |
| 3 | 21099291 | In parallel, we also investigated the subcellular localization of polypyrimidine tract-binding protein 1 (PTBP1), whose nucleocytoplasmic translocation is involved in the rapid posttranscriptional up-regulation of insulin biosynthesis following islet stimulation with glucose and GLP-1. |