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Gene Information
Gene symbol: RARA
Gene name: retinoic acid receptor, alpha
HGNC ID: 9864
Synonyms: RAR, NR1B1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CAPN1 | 1 hits |
| 2 | CAPN2 | 1 hits |
| 3 | GDNF | 1 hits |
| 4 | MLL2 | 1 hits |
| 5 | MLL3 | 1 hits |
| 6 | RBP1 | 1 hits |
| 7 | VEGFA | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17021013 | Activating signal cointegrator-2 (ASC-2), a coactivator of multiple transcription factors that include retinoic acid receptor (RAR), associates with histone H3-K4 methyltranferases (H3K4MTs) MLL3 and MLL4 in mixed-lineage leukemia. |
| 2 | 17460283 | In addition, RARalpha agonists significantly abrogated the upregulation of calpain 2 induced by H(2)O(2), which is a potential etiological contributor to the diabetic cataract, whereas H(2)O(2) had no effect on calpain 1. |
| 3 | 17470563 | Here, we demonstrate that retinoic acid receptor (RAR)alpha stimulants preferentially act on glial cells rather than endothelial cells, resulting in the enhanced expression of glial cell line-derived neurotrophic factor (GDNF) through recruitment of the RARalpha-driven trans-acting coactivator to the 5'-flanking region of the gene promoter. |
| 4 | 17470563 | Conversely, RARalpha decreases expression of vascular endothelial growth factor (VEGF)/vascular permeability factor. |
| 5 | 19114589 | In adipocytes, the overexpression of CRBP1 enhanced (4- to 5-fold) the activity of promoters containing response elements for retinol-dependent nuclear receptors [retinoic acid receptor (RAR) and retinoid X receptor (RXR)] or peroxisome proliferator-activated receptors (PPAR). |