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Gene Information
Gene symbol: RASA1
Gene name: RAS p21 protein activator (GTPase activating protein) 1
HGNC ID: 9871
Synonyms: GAP, CM-AVM, p120GAP, p120RASGAP
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | MAPK1 | 1 hits |
| 2 | NME1 | 1 hits |
| 3 | RAC1 | 1 hits |
| 4 | STAT1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 10611312 | The GAP activity of nm23 was specific for Rad, was absent with the S105N putative dominant negative mutant of Rad, and was reduced with mutations of nm23. |
| 2 | 12730241 | Insulin receptor-phosphorylated IRS5/DOK4 associates with RasGAP, Crk, Src, and Fyn, but not phosphatidylinositol 3-kinase p85, Grb2, SHP-2, Nck, or phospholipase Cgamma Src homology 2 domains, and activates MAPK in cells. |
| 3 | 18260110 | Mutations in the BTK, SH2D1A, ZAP70, STAT1, and STAT5B genes have been shown to cause diverse immunodeficiencies, whereas the mutations in RASA1 and PIK3R1 genes lead to basal carcinoma and diabetes, respectively. |
| 4 | 21969604 | Mutation of the catalytic arginine of the GAP domain of RhoGAP22 potentiated growth factor-stimulated Rac1 GTP loading. |