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Gene Information
Gene symbol: SAA
Gene name: serum amyloid A1 cluster
HGNC ID: 10512
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ADIPOQ | 1 hits |
| 2 | ALB | 1 hits |
| 3 | CRP | 1 hits |
| 4 | IDDM2 | 1 hits |
| 5 | IL6 | 1 hits |
| 6 | IL8 | 1 hits |
| 7 | INS | 1 hits |
| 8 | LPAL2 | 1 hits |
| 9 | NOX5 | 1 hits |
| 10 | SLC2A4 | 1 hits |
| 11 | TNF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 3069282 | Elevated SAA-levels were either associated with raised CRP, indicating a non-specific acute phase reaction, or were markedly diminished or normalized in a six-month follow-up, in spite ongoing pump therapy. |
| 2 | 3069282 | Increased SAA-concentrations did not correlate with sex or age of patients, diabetes duration, diabetes type, duration of pump treatment, route of insulin, insulin preparation, catheter material and pump model, indicating that pump treatment does not stimulate a specific amyloidogenic reaction. |
| 3 | 7535207 | However, SAA levels in patients with NIDDM increased significantly, with increase of urinary albumin excretion (p = 0.027). |
| 4 | 12397025 | SAA catabolism, as measured by fed-state sulfate production, may be a convenient and useful method to determine the extent of whole body protein dysregulation in IDDM. |
| 5 | 16868887 | Reduction of hyperglycaemia results in decreased sE-selectin, A1GP, sICAM-1 and IL6, while other inflammatory factors including CRP, SAA and adiponectin are not affected. |
| 6 | 16737350 | SAA treatment of vascular endothelial cells and monocytes markedly increased the production of inflammatory cytokines, e.g., interleukin (IL)-6, IL-8, tumor necrosis factor alpha, and monocyte chemoattractant protein-1. |
| 7 | 19474523 | To assess the potential impact of A-SAA on insulin resistance, we treated 3T3-L1 adipocytes with recombinant human SAA (Rh-SAA) and found that Rh-SAA attenuated cellular insulin sensitivity, up-regulated the level of phosphor-JNK, and down-regulated the level of phosphotyrosine-IRS-1 and the expression of glucose transporter 4 (GLUT4) in 3T3-L1 adipocytes. |
| 8 | 19758820 | The aim of this study was to characterize the association between adipocyte enlargement and circulating levels of serum amyloid A (SAA). |
| 9 | 19758820 | SAA levels were weakly but positively correlated with BMI (p=0.043) and % body fat (p=0.027) in all subjects as well as subcutaneous adipocyte diameter (p=0.034) in women. |
| 10 | 20875380 | The aim of this study was to investigate the effects of ezetimibe on high-density lipoprotein (HDL) subspecies and serum amyloid A (SAA), an apolipoprotein mainly bound and transported by HDL particles, in patients with end-stage renal disease (ERSD), a condition typically characterized by high SAA- and low HDL-cholesterol (C ) levels. 26 ERSD patients receiving hemodialysis (HD) were given ezetimibe (10 mg/d) for 6 - 8 weeks. |
| 11 | 21175596 | In addition, the expression of p47-phox was up-regulated by SAA (P < 0·001) and diphenyliodonium (DPI), a nicotinamide adenine dinucleotide phosphate (NADPH) oxidase inhibitor, reduced the release of O(2) (-) by 50%. |
| 12 | 21327868 | Circulating SAA and SAP did not decrease in either insulin-treated group, but IL-6 levels fell in the glargine-treated mice. |
| 13 | 21327868 | While chronic insulin administration did not decrease SAA and SAP, administration of glargine but not detemir insulin improved dyslipidaemia, IL-6 levels and atherosclerosis, and both insulins reduced macrophage accumulation in visceral adipose tissue. |