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Gene Information
Gene symbol: SLC6A3
Gene name: solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
HGNC ID: 11049
Synonyms: DAT
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | IGF2 | 1 hits |
| 2 | INS | 1 hits |
| 3 | SLC6A2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 8930308 | We have previously reported that chronic elevation of insulin in the CNS of rats results in opposing changes of the mRNA expression for the norepinephrine transporter (NET; decreased) and the dopamine transporter (DAT; increased). |
| 2 | 8930308 | In the present study we tested the hypothesis that a chronic depletion of insulin would result in opposite changes of NET and DAT mRNA expression, from those observed with chronic elevation of insulin. |
| 3 | 8930308 | In the diabetic animals, NET mRNA was significantly elevated (159 +/- 22% of average control level) while DAT mRNA was non-significantly decreased (78 +/- 9% of average control level). |
| 4 | 11147788 | Allelic variation in the size of the insulin (INS) variable number tandem repeat (VNTR) correlates with the expression of both INS in the pancreas and thymus and IGF2 (the gene downstream of INS) in the placenta. |
| 5 | 18155695 | Experimentally-induced diabetes can modify the behavioral and neurochemical effects of drugs acting on dopamine systems, possibly through insulin-related regulation of dopamine transporter activity. |