- About
- Home
- Introduction
- Statistics
- Programs
- Dignet
- Gene
- GenePair
- Help & Docs
- Documents
- Help
- FAQs
- Links
- Acknowledge
- Disclaimer
- Contact Us
Gene Information
Gene symbol: STEAP4
Gene name: STEAP family member 4
HGNC ID: 21923
Synonyms: FLJ23153, TIARP, STAMP2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AKT1 | 1 hits |
| 2 | BCL2A1 | 1 hits |
| 3 | INS | 1 hits |
| 4 | IRS1 | 1 hits |
| 5 | LTF | 1 hits |
| 6 | MRC1 | 1 hits |
| 7 | SLC2A4 | 1 hits |
| 8 | SREBF1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20382686 | The six-transmembrane protein of prostate 2 (STAMP2) has been shown to be involved in insulin resistance in animal models, but in humans, its role is far from understood. |
| 2 | 21647634 | Western blotting was performed to determine STEAP4 expression, to assess translocation of insulin-sensitive glucose transporter 4 (GLUT4), and to measure phosphorylation and total protein content of insulin-signaling proteins. |
| 3 | 21647634 | In conclusion, (i) STEAP4 regulates the function of IRS-1, PI3K, and Akt and decreases insulin-induced GLUT4 translocation and glucose uptake; (ii) ROS-related mitochondrial dysfunction may be related to a reduced IRS-1 correlation with the PI3K signaling pathway, leading to insulin resistance. |
| 4 | 21849520 | In addition, STAMP2 gene expression was positively associated with lipogenic (FASN, ACC1, SREBP1, THRSP14, TR?, and TR?1), CAV1, IRS1, GLUT4, and CD206 gene expression. |
| 5 | 21295959 | In both subcutaneous and visceral preadipocytes, lactoferrin (1 and 10 ?M) increased adipogenic gene expressions and protein levels (fatty acid synthase, PPAR?, FABP4, ADIPOQ, ACC and STAMP2) and decreased inflammatory markers (IL8, IL6 and MCP1) dose-dependently in parallel to increased insulin-induced (Ser473)AKT phosphorylation. |