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Gene Information
Gene symbol: TCEAL1
Gene name: transcription elongation factor A (SII)-like 1
HGNC ID: 11616
Synonyms: p21, pp21, SIIR, P21
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | IGF1 | 1 hits |
| 2 | KLRG1 | 1 hits |
| 3 | MAP3K1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21190012 | At P2 most beta cell genes were expressed at about 10% of adult, but by P7 Pdx1 and Neurod1 no longer differ from adult; by contrast, Mafa expression remained significantly lower than adult through P21. |
| 2 | 12647305 | MG rendered these cells resistant to the mitogenic action of IGF-I, and this was associated with stronger and prolonged activation of ERK and over-expression of P21(Waf1/Cip1). |
| 3 | 12647305 | These results suggested that the alteration of intracellular milieu induced by MG through a MEKK1-mediated and PI3K/PKC/Raf-1-independent pathway resulted in the modification of cell response to IGF-I for p21(Waf1/Cip1)-mediated growth arrest, which may be one of the crucial mechanisms for MG to promote the development of chronic clinical complications in diabetes. |