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Gene Information
Gene symbol: VAMP2
Gene name: vesicle-associated membrane protein 2 (synaptobrevin 2)
HGNC ID: 12643
Synonyms: VAMP-2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | INS | 1 hits |
| 2 | SLC2A4 | 1 hits |
| 3 | SNAP23 | 1 hits |
| 4 | STX4 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16517145 | Gene expression profiling using microarray and real-time PCR show significant changes in the expression of four genes--Vamp2, Dok1, Glut4 and Mapk14--involved in insulin signaling. |
| 2 | 19188424 | Munc18c depletion ablated the glucose-stimulated VAMP2-Syntaxin 4 association as well as Syntaxin 4 activation, correlating with the deficit in insulin release. |
| 3 | 20006577 | We have now shown that depletion of the vesicle SNARE (v-SNARE) VAMP2 by RNA interference in 3T3-L1 adipocytes inhibited the fusion of GLUT4 vesicles with the plasma membrane but did not affect tethering of the vesicles to the membrane. |
| 4 | 20006577 | Our results indicate that the t-SNAREs syntaxin4 and SNAP23 are indispensable for the tethering of GLUT4 vesicles to the plasma membrane, whereas the v-SNARE VAMP2 is not required for this step but is essential for the subsequent fusion event. |
| 5 | 20085539 | Glycosphingolipid depletion also enhanced the insulin-induced translocation of VAMP2 (vesicle-associated membrane protein 2), but not the transferrin receptor or cellubrevin, indicating that the effect of glycosphingolipids was specific to VAMP2-positive GSVs. |