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Gene Information
Gene symbol: WNT5A
Gene name: wingless-type MMTV integration site family, member 5A
HGNC ID: 12784
Synonyms: hWNT5A
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | GSK3B | 1 hits |
| 2 | SFRP1 | 1 hits |
| 3 | SPP1 | 1 hits |
| 4 | WNT2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15754042 | Canonical WNTs (WNT2, WNT2B, etc) activate the beta-catenin-TCF pathway to induce carcinogenesis, while non-canonical WNTs (WNT5A, WNT11, etc) activate the planar cell polarity (PCP) pathway to induce cell motility and metastasis. |
| 2 | 16943306 | Suppression of GSK-3beta activation or increase in nuclear beta-catenin by transfection of Wnt4 or Wnt5a or stable beta-catenin (S33Y) reversed Akt activation and reduced the high glucose-mediated caspase-3 cleavage and cell apoptosis. |
| 3 | 20032469 | Activation of this noncanonical pathway resulted in the induction of osteopontin expression further indicating pro-osteogenic effects of WNT-5a. |
| 4 | 21344486 | While WNT5A, FZD5, and DKK1 were highly expressed in PC3 cells, WNT1 and SFRP1 mRNA levels were higher in DU145 cells. |