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Gene Pair Information
Gene Pair: MARCH1, CD83
Related Sentences
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PMID |
Sentence |
1 |
21220452
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Using mice with an N-ethyl-N-nitrosourea-induced mutation eliminating the transmembrane (TM) region of CD83, we found that the TM domain of CD83 enhances MHC class II and CD86 expression by blocking MHC class II association with the ubiquitin ligase MARCH1.
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2 |
21220452
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The TM region of CD83 blocks interleukin 10-driven, MARCH1-dependent ubiquitination and degradation of MHC class II and CD86 in DCs.
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