Ignet

Gene Pair: ADIPOQ, MAPK1

Related Sentences

#	PMID	Sentence
1	20802255	At the molecular level, adiponectin decreased high glucose-induced accumulation of intracellular reactive oxygen species and consequently suppressed activation of p38 MAP kinase (MAPK) and expression of the senescence marker p16(INK4A).
2	20339310	The prolonged treatment of mature 3T3-L1 adipocytes with palmitate, a kind of saturated free fatty acid, reduced adiponectin expression at both mRNA level and protein level, accompanied with the enhanced phosphorylation of PKC? and extracellular signal-regulated kinase (ERK), and the impaired expression of peroxisome proliferator-activated receptor ?2 (PPAR?2) mRNA.
3	20339310	Either PD98059, an ERK inhibitor or PKC? pseudosubstrate, a specific PKC? inhibitor, restored palmiate-inhibited PPAR?2 mRNA expression and subsequent adiponectin expression.