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Gene Pair Information
Gene Pair: AGT, SMAD2
Related Sentences
# |
PMID |
Sentence |
1 |
15840669
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The expression of alpha3(IV) collagen was influenced by the TGF-beta system, but AngII did not increase the podocyte's production of TGF-beta1 ligand; rather, it increased the expression of the TGF-beta type II receptor and activated the TGF-beta signalling system through Smad2.
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2 |
16556868
|
Finally, activation of Smad3 but not Smad2 was a key and necessary mechanism of Ang II-induced vascular fibrosis because Ang II induced Smad3/4 promoter activities and collagen matrix expression was abolished in VSMCs null for Smad3 but not Smad2.
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3 |
16556868
|
Activation of Smad3 but not Smad2 is a key mechanism by which Ang II mediates arteriosclerosis.
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