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Gene Pair Information

Gene Pair: AGT, SMAD2

Related Sentences

# PMID Sentence
1 15840669 The expression of alpha3(IV) collagen was influenced by the TGF-beta system, but AngII did not increase the podocyte's production of TGF-beta1 ligand; rather, it increased the expression of the TGF-beta type II receptor and activated the TGF-beta signalling system through Smad2.
2 16556868 Finally, activation of Smad3 but not Smad2 was a key and necessary mechanism of Ang II-induced vascular fibrosis because Ang II induced Smad3/4 promoter activities and collagen matrix expression was abolished in VSMCs null for Smad3 but not Smad2.
3 16556868 Activation of Smad3 but not Smad2 is a key mechanism by which Ang II mediates arteriosclerosis.