Ignet

Gene Pair: AKR1B1, COL1A1

Related Sentences

#	PMID	Sentence
1	2836250	Treatment with AA or an aldose reductase inhibitor may prevent some of the diabetic complications with underlying collagen abnormalities.
2	8019906	Aldose reductase inhibitors like sorbinil do prevent basement membrane thickening and type IV collagen overproduction.
3	8781759	In order to analyse the importance of the polyol pathway in the development of the collagen metabolism alterations seen in diabetic angiopathy and their prevention by aldose reductase inhibitors, we have studied the effects of sorbinil on the high glucose-induced stimulation of type IV collagen biosynthesis in human umbilical vein endothelial cells.