Ignet

Gene Pair: BCL2L11, MAPK8

Related Sentences

#	PMID	Sentence
1	21984578	RESEARCH DESIGN AND METHODS Small interfering RNAs were used to inhibit PTPN2, STAT1, Bim, and Jun NH(2)-terminal kinase 1 (JNK1) expression.
2	21984578	There was also an increase in Bim phosphorylation that was at least in part regulated by JNK1.
3	21984578	CONCLUSIONS The present findings suggest that local IFN production may interact with a genetic factor (PTPN2) to induce aberrant proapoptotic activity of the BH3-only protein Bim, resulting in increased ?-cell apoptosis via JNK activation and the intrinsic apoptotic pathway.