|
Gene Pair Information
Gene Pair: BTC, ERBB2
Related Sentences
# |
PMID |
Sentence |
1 |
21897861
|
Immunoprecipitation and western blotting analysis showed that BTC treatment of MIN-6 cells induced phosphorylation of only ErbB-1 and ErbB-2 among the four EGF receptors.
|
2 |
21897861
|
BTC treatment increased mRNA and protein levels of insulin receptor substrate-2 (IRS-2), and this was blocked by the ErbB-1 and ErbB-2 inhibitors.
|
3 |
21897861
|
These results suggest that BTC exerts proliferative activity on beta cells through the activation of ErbB-1 and ErbB-2 receptors, which may increase IRS-2 expression, contributing to the regeneration of beta cells.
|
|