Ignet

Gene Pair: BTC, IRS2

Related Sentences

#	PMID	Sentence
1	21897861	BTC treatment increased mRNA and protein levels of insulin receptor substrate-2 (IRS-2), and this was blocked by the ErbB-1 and ErbB-2 inhibitors.
2	21897861	Inhibition of IRS-2 by siRNA blocked cell cycle progression induced by BTC treatment.
3	21897861	These results suggest that BTC exerts proliferative activity on beta cells through the activation of ErbB-1 and ErbB-2 receptors, which may increase IRS-2 expression, contributing to the regeneration of beta cells.