|
Gene Pair Information
Gene Pair: CRTC2, INS
Related Sentences
# |
PMID |
Sentence |
1 |
17805301
|
Here we show in mice that insulin inhibits gluconeogenic gene expression during re-feeding by promoting the phosphorylation and ubiquitin-dependent degradation of TORC2.
|
2 |
17805301
|
Insulin disrupts TORC2 activity by induction of the Ser/Thr kinase SIK2, which we show here undergoes AKT2-mediated phosphorylation at Ser 358.
|
3 |
21965330
|
This oxidative stress disrupted mTorc2 and impaired mTorc2/Akt signaling in other insulin-sensitive organs, leading to insulin resistance that could be largely reversed with antioxidant treatment.
|
|