Ignet

Gene Pair: GCK, FASN

Related Sentences

#	PMID	Sentence
1	15711641	Decreased IRS-1 was also associated with a decrease in glucokinase expression and a trend toward increased blood glucose, whereas knockdown of IRS-2 resulted in the upregulation of lipogenic enzymes SREBP-1c and fatty acid synthase, as well as increased hepatic lipid accumulation.
2	21490074	Furthermore, hepatic GCK mRNA expression is associated with lipogenic gene expression (fatty acid synthase, r = 0.49, P = 0.0003; acetyl-coenzyme A carboxylase-?, r = 0.44, P = 0.0015, and acetyl-coenzyme A carboxylase-?, r = 0.48, P = 0.0004) and the de novo lipogenesis index (r = 0.36, P = 0.01).