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Gene Pair Information
Gene Pair: GPAM, SREBF1
Related Sentences
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PMID |
Sentence |
1 |
20200319
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In ob/ob mice, sterol regulatory element binding protein 1 (SREBP1) mediates the induction of steatosis by upregulating target genes, including glycerol-3-phosphate acyltransferase-1 (Gpat1), which catalyzes the first and committed step in the pathway of glycerolipid synthesis.
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2 |
20200319
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They also show that the SREBP1-mediated induction of hepatic steatosis in ob/ob mice requires Gpat1.
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